With the volume/site license version of EndNote, a network administrator can use mass installation to install EndNote on multiple machines.
First, unlock the installer to generate an EN Inst.msi file and a license.dat file. See Unlocking the Volume/Site License Installer.
Deploy EN Inst.msi and license.dat together.
You can deploy in any way you want, but make sure the two files are in the same directory when executed. You could zip the two files to distribute them to end users, you could create a Group Policy deployment where both files are delivered to the same location on the target machine, or you could drop the two files in a shared network location from which users execute the installer.
(Optional) For each user account, you can configure EndNote as the default citation manager in Word.
First, unlock the installer to generate an EN Inst.msi file and a license.dat file. See Unlocking the Volume/Site License Installer.
Distribute both the EN Inst.msi and license.dat file to the user. For example, you can copy them to a shared network drive or a CD.
The user should then copy the two files, EN Inst.msi and license.dat to the same folder on his/her individual computer.
The user should log on to the computer with administrative rights, and then run EN Inst.msi to install the EndNote program. (Do not run in Admin mode this time.)
(Optional) For each user account, you can configure EndNote as the default citation manager in Word.